Harnessing the Immune System to Improve Human Health

Harnessing the Immune System to Improve Human Health

Pipeline

Inimmune’s focus is to discover and develop disease-modifying immunotherapies. Currently, our pipeline includes two clinical-stage Toll-like receptor (TLR) agonists in immuno-oncology and allergy. Both of these TLR agonists generated disease-modifying therapeutic responses in pre-clinical models. Late-stage pre-clinical programs are focused on developing innate immune agonists as next-generation vaccine adjuvants and discovery-stage projects are centered around novel, non-TLR innate immune agonists and antagonists.

Pipeline

Inimmune’s focus is to discover and develop disease-modifying immunotherapies. Currently, our pipeline includes two clinical-stage Toll-like receptor (TLR) agonists in immuno-oncology and allergy. Both of these TLR agonists generated disease-modifying therapeutic responses in pre-clinical models. Late-stage pre-clinical programs are focused on developing innate immune agonists as next-generation vaccine adjuvants and discovery-stage projects are centered around novel, non-TLR innate immune agonists and antagonists.

Our Clinical Trials

Inimmune has completed a Phase I clinical trial evaluating the safety and tolerability of INI-2004 (a TLR4 agonist) as a treatment for allergic rhinitis. Inimmune also has an ongoing Phase I clinical trial evaluating the safety and tolerability of INI-4001 (a TLR7/8 agonist) as a cancer treatment, both alone and in combination with existing checkpoint inhibitors.

Changing The Landscape

Inimmune is a clinical-stage, fast-moving innovative biotech company focused on the discovery and development of novel immunotherapeutics for cancer, allergy, autoimmunity, and vaccines. Inimmune has a deep pipeline consisting of two clinical-stage assets and early and late pre-clinical assets, all poised to change the landscape of immunotherapy and vaccine adjuvants.

Partnerships & Collaborations

We partner with some of the best universities and biotech companies. Want to co-create and develop novel immunotherapeutics to improve human health?

SPI Pharma_171x50 (2)
We have partnered with SPI Pharma, Inc. to develop and commercialize innovative vaccine adjuvant systems. SPI Pharma specializes in drug development services, having participated in over 60 commercially launched and marketed drugs globally.
Boston Childrens Hospital_99x40
Inimmune collaborates on multiple adjuvant discovery and development projects with the labs of Drs. Ofer Levy and David Dowling. Current projects are focused on the development of adjuvanted opioid and pertussis vaccines.
Cleveland Clinic_158x40
We have a long-standing collaboration with Dr. Ted Ross at Cleveland Clinic working on developing an adjuvanted universal influenza vaccine.
Columbia University_230x35
As part of our opioid vaccine development efforts, we are collaborating with Dr. Sandra Comer at Columbia University. Dr. Comer is a leader in the field of opioid vaccine clinical trials.
Duke University_103x45
For our work developing a sublingual food allergy treatment, we are collaborating with Drs. Herman Staats and Brandi Johnson-Weaver.
Icahn School_220x40
We collaborate with Drs. Florian Krammer and Adolfo Garcia-Sastre on multiple projects focused on developing new adjuvanted influenza vaccines.
Intrommune_200x31
We are collaborating with Intrommune to co-develop an adjuvanted food allergy treatment. We are exploring the combination of our clinical-stage TLR4 agonist, INI-2004, with Intrommune’s clinical-stage oral mucosal immunotherapy, INT301.
Oregon Health Science University_200x50
At OHSU, we collaborate with Dr Victor DeFilippis on our STING adjuvant discovery project.
University of Chicago_159x40
We are collaborating with Dr. Aaron Esser-Kahn on discovering novel combination adjuvants.
University of Montana_212x40
Inimmune collaborates with the Center for Translational Medicine Adjuvant Research Team on multiple projects past and present, including our opioid vaccine, TRAC478 vaccine adjuvant, and INI-1098 vaccine adjuvant development projects.
University of North Carolina_164x45
We collaborate with Drs. Mike Kulis and Johanna Smeekens at UNC on the development of a sublingual food allergy therapy.
University of Washington_158x40
At UW, we collaborate with Dr. Marco Pravetoni on our opioid vaccine development project and Dr. Michael Gale on an early-stage adjuvant discovery project.

Careers

We are a biotech company founded by pharmaceutical industry veterans, focused on developing the next generation of vaccines and immunotherapeutics. We have extensive expertise in synthetic and process chemistry, drug formulation, immunology, and clinical translation. Our goal at Inimmune is to recruit, hire, and maintain a diverse workforce. Equal employment opportunity is good business. Equal opportunity applies to all aspects of our employment, including recruitment, selection, hiring, training, transfer, promotion, termination, compensation, and benefits.