{"id":609,"date":"2024-05-30T19:04:41","date_gmt":"2024-05-30T19:04:41","guid":{"rendered":"https:\/\/inimmune.com\/?page_id=609"},"modified":"2024-08-10T17:51:42","modified_gmt":"2024-08-10T17:51:42","slug":"trac478-vaccine-adjuvant","status":"publish","type":"page","link":"https:\/\/inimmune.com\/?page_id=609","title":{"rendered":"TRAC478 Vaccine Adjuvant"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"609\" class=\"elementor elementor-609\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a6cf495 e-flex e-con-boxed e-con e-parent\" data-id=\"a6cf495\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1b6a25f elementor-widget elementor-widget-heading\" data-id=\"1b6a25f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">TRAC478 Vaccine Adjuvant<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-fad5fe8 elementor-widget elementor-widget-text-editor\" data-id=\"fad5fe8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>A new combination adjuvant approach<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-93f4f2e elementor-widget elementor-widget-image\" data-id=\"93f4f2e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"534\" src=\"https:\/\/inimmune.com\/wp-content\/uploads\/2024\/05\/microscope-with-test-1024x683.jpg\" class=\"attachment-large size-large wp-image-614\" alt=\"\" srcset=\"https:\/\/inimmune.com\/wp-content\/uploads\/2024\/05\/microscope-with-test-1024x683.jpg 1024w, https:\/\/inimmune.com\/wp-content\/uploads\/2024\/05\/microscope-with-test-300x200.jpg 300w, https:\/\/inimmune.com\/wp-content\/uploads\/2024\/05\/microscope-with-test-768x513.jpg 768w, https:\/\/inimmune.com\/wp-content\/uploads\/2024\/05\/microscope-with-test.jpg 1320w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2a66448 elementor-widget elementor-widget-text-editor\" data-id=\"2a66448\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>TRAC478 is a new combination adjuvant approach in which INI-2002, a TLR4 adjuvant, and INI-4001, a TLR7\/8 adjuvant are used together to generate synergistic immune responses. Pre-clinically, TRAC478 results in strong Th1-biased antibody and T cell responses and is efficacious in influenza challenge models. TRAC478 can be used with a number of different vaccine formulations, each of which influences the adjuvant-mediated immune response to better tailor the response to protect against a particular pathogen.\u00a0<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0edfef6 elementor-widget elementor-widget-heading\" data-id=\"0edfef6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Upcoming Clinical Trial<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2dee901 elementor-widget elementor-widget-text-editor\" data-id=\"2dee901\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Both INI-2002 and INI-4001 have been manufactured under cGMP conditions and cGMP production of of a TRAC478 emulsion drug product is underway. The first human use of TRAC478 is expected in a 2025 NIH-funded influenza vaccine clinical trial as part of the CIVICs (<a href=\"https:\/\/www.niaidcivics.org\/\" target=\"_blank\" rel=\"noopener\">Collaborative Influenza Vaccine Innovation Centers<\/a>) program.\u00a0<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>TRAC478 Vaccine Adjuvant A new combination adjuvant approach TRAC478 is a new combination adjuvant approach in which INI-2002, a TLR4 adjuvant, and INI-4001, a TLR7\/8 adjuvant are used together to generate synergistic immune responses. Pre-clinically, TRAC478 results in strong Th1-biased antibody and T cell responses and is efficacious in influenza challenge models. TRAC478 can be [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-609","page","type-page","status-publish","hentry"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.8 - aioseo.com -->\n\t<meta name=\"description\" content=\"TRAC478 Vaccine Adjuvant A new combination adjuvant approach TRAC478 is a new combination adjuvant approach in which INI-2002, a TLR4 adjuvant, and INI-4001, a TLR7\/8 adjuvant are used together to generate synergistic immune responses. Pre-clinically, TRAC478 results in strong Th1-biased antibody and T cell responses and is efficacious in influenza challenge models. TRAC478 can be\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<link rel=\"canonical\" href=\"https:\/\/inimmune.com\/?page_id=609\" \/>\n\t<meta name=\"generator\" content=\"All in One SEO (AIOSEO) 4.9.8\" \/>\n\t\t<meta property=\"og:locale\" content=\"en_US\" \/>\n\t\t<meta property=\"og:site_name\" content=\"Inimmune - Harnessing the Immune System to Improve Human Health\" \/>\n\t\t<meta property=\"og:type\" content=\"article\" \/>\n\t\t<meta property=\"og:title\" content=\"TRAC478 Vaccine Adjuvant - Inimmune\" \/>\n\t\t<meta property=\"og:description\" content=\"TRAC478 Vaccine Adjuvant A new combination adjuvant approach TRAC478 is a new combination adjuvant approach in which INI-2002, a TLR4 adjuvant, and INI-4001, a TLR7\/8 adjuvant are used together to generate synergistic immune responses. Pre-clinically, TRAC478 results in strong Th1-biased antibody and T cell responses and is efficacious in influenza challenge models. TRAC478 can be\" \/>\n\t\t<meta property=\"og:url\" content=\"https:\/\/inimmune.com\/?page_id=609\" \/>\n\t\t<meta property=\"article:published_time\" content=\"2024-05-30T19:04:41+00:00\" \/>\n\t\t<meta property=\"article:modified_time\" content=\"2024-08-10T17:51:42+00:00\" \/>\n\t\t<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n\t\t<meta name=\"twitter:title\" content=\"TRAC478 Vaccine Adjuvant - Inimmune\" \/>\n\t\t<meta name=\"twitter:description\" content=\"TRAC478 Vaccine Adjuvant A new combination adjuvant approach TRAC478 is a new combination adjuvant approach in which INI-2002, a TLR4 adjuvant, and INI-4001, a TLR7\/8 adjuvant are used together to generate synergistic immune responses. Pre-clinically, TRAC478 results in strong Th1-biased antibody and T cell responses and is efficacious in influenza challenge models. TRAC478 can be\" \/>\n\t\t<script type=\"application\/ld+json\" class=\"aioseo-schema\">\n\t\t\t{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/inimmune.com\\\/?page_id=609#breadcrumblist\",\"itemListElement\":[{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/inimmune.com#listItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/inimmune.com\",\"nextItem\":{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/inimmune.com\\\/?page_id=609#listItem\",\"name\":\"TRAC478 Vaccine Adjuvant\"}},{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/inimmune.com\\\/?page_id=609#listItem\",\"position\":2,\"name\":\"TRAC478 Vaccine Adjuvant\",\"previousItem\":{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/inimmune.com#listItem\",\"name\":\"Home\"}}]},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/inimmune.com\\\/#organization\",\"name\":\"My Blog\",\"description\":\"Harnessing the Immune System to Improve Human Health\",\"url\":\"https:\\\/\\\/inimmune.com\\\/\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/inimmune.com\\\/?page_id=609#webpage\",\"url\":\"https:\\\/\\\/inimmune.com\\\/?page_id=609\",\"name\":\"TRAC478 Vaccine Adjuvant - Inimmune\",\"description\":\"TRAC478 Vaccine Adjuvant A new combination adjuvant approach TRAC478 is a new combination adjuvant approach in which INI-2002, a TLR4 adjuvant, and INI-4001, a TLR7\\\/8 adjuvant are used together to generate synergistic immune responses. Pre-clinically, TRAC478 results in strong Th1-biased antibody and T cell responses and is efficacious in influenza challenge models. TRAC478 can be\",\"inLanguage\":\"en-US\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/inimmune.com\\\/#website\"},\"breadcrumb\":{\"@id\":\"https:\\\/\\\/inimmune.com\\\/?page_id=609#breadcrumblist\"},\"datePublished\":\"2024-05-30T19:04:41+00:00\",\"dateModified\":\"2024-08-10T17:51:42+00:00\"},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/inimmune.com\\\/#website\",\"url\":\"https:\\\/\\\/inimmune.com\\\/\",\"name\":\"My Blog\",\"description\":\"Harnessing the Immune System to Improve Human Health\",\"inLanguage\":\"en-US\",\"publisher\":{\"@id\":\"https:\\\/\\\/inimmune.com\\\/#organization\"}}]}\n\t\t<\/script>\n\t\t<!-- All in One SEO -->\n\n","aioseo_head_json":{"title":"TRAC478 Vaccine Adjuvant - Inimmune","description":"TRAC478 Vaccine Adjuvant A new combination adjuvant approach TRAC478 is a new combination adjuvant approach in which INI-2002, a TLR4 adjuvant, and INI-4001, a TLR7\/8 adjuvant are used together to generate synergistic immune responses. Pre-clinically, TRAC478 results in strong Th1-biased antibody and T cell responses and is efficacious in influenza challenge models. TRAC478 can be","canonical_url":"https:\/\/inimmune.com\/?page_id=609","robots":"max-image-preview:large","keywords":"","webmasterTools":{"miscellaneous":""},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"BreadcrumbList","@id":"https:\/\/inimmune.com\/?page_id=609#breadcrumblist","itemListElement":[{"@type":"ListItem","@id":"https:\/\/inimmune.com#listItem","position":1,"name":"Home","item":"https:\/\/inimmune.com","nextItem":{"@type":"ListItem","@id":"https:\/\/inimmune.com\/?page_id=609#listItem","name":"TRAC478 Vaccine Adjuvant"}},{"@type":"ListItem","@id":"https:\/\/inimmune.com\/?page_id=609#listItem","position":2,"name":"TRAC478 Vaccine Adjuvant","previousItem":{"@type":"ListItem","@id":"https:\/\/inimmune.com#listItem","name":"Home"}}]},{"@type":"Organization","@id":"https:\/\/inimmune.com\/#organization","name":"My Blog","description":"Harnessing the Immune System to Improve Human Health","url":"https:\/\/inimmune.com\/"},{"@type":"WebPage","@id":"https:\/\/inimmune.com\/?page_id=609#webpage","url":"https:\/\/inimmune.com\/?page_id=609","name":"TRAC478 Vaccine Adjuvant - Inimmune","description":"TRAC478 Vaccine Adjuvant A new combination adjuvant approach TRAC478 is a new combination adjuvant approach in which INI-2002, a TLR4 adjuvant, and INI-4001, a TLR7\/8 adjuvant are used together to generate synergistic immune responses. Pre-clinically, TRAC478 results in strong Th1-biased antibody and T cell responses and is efficacious in influenza challenge models. TRAC478 can be","inLanguage":"en-US","isPartOf":{"@id":"https:\/\/inimmune.com\/#website"},"breadcrumb":{"@id":"https:\/\/inimmune.com\/?page_id=609#breadcrumblist"},"datePublished":"2024-05-30T19:04:41+00:00","dateModified":"2024-08-10T17:51:42+00:00"},{"@type":"WebSite","@id":"https:\/\/inimmune.com\/#website","url":"https:\/\/inimmune.com\/","name":"My Blog","description":"Harnessing the Immune System to Improve Human Health","inLanguage":"en-US","publisher":{"@id":"https:\/\/inimmune.com\/#organization"}}]},"og:locale":"en_US","og:site_name":"Inimmune - Harnessing the Immune System to Improve Human Health","og:type":"article","og:title":"TRAC478 Vaccine Adjuvant - Inimmune","og:description":"TRAC478 Vaccine Adjuvant A new combination adjuvant approach TRAC478 is a new combination adjuvant approach in which INI-2002, a TLR4 adjuvant, and INI-4001, a TLR7\/8 adjuvant are used together to generate synergistic immune responses. Pre-clinically, TRAC478 results in strong Th1-biased antibody and T cell responses and is efficacious in influenza challenge models. TRAC478 can be","og:url":"https:\/\/inimmune.com\/?page_id=609","article:published_time":"2024-05-30T19:04:41+00:00","article:modified_time":"2024-08-10T17:51:42+00:00","twitter:card":"summary_large_image","twitter:title":"TRAC478 Vaccine Adjuvant - Inimmune","twitter:description":"TRAC478 Vaccine Adjuvant A new combination adjuvant approach TRAC478 is a new combination adjuvant approach in which INI-2002, a TLR4 adjuvant, and INI-4001, a TLR7\/8 adjuvant are used together to generate synergistic immune responses. Pre-clinically, TRAC478 results in strong Th1-biased antibody and T cell responses and is efficacious in influenza challenge models. TRAC478 can be"},"aioseo_meta_data":{"post_id":"609","title":null,"description":null,"keywords":null,"keyphrases":{"focus":{"keyphrase":"","score":0,"analysis":{"keyphraseInTitle":{"score":0,"maxScore":9,"error":1}}},"additional":[]},"primary_term":null,"canonical_url":null,"og_title":null,"og_description":null,"og_object_type":"default","og_image_type":"default","og_image_url":null,"og_image_width":null,"og_image_height":null,"og_image_custom_url":null,"og_image_custom_fields":null,"og_video":"","og_custom_url":null,"og_article_section":null,"og_article_tags":null,"twitter_use_og":false,"twitter_card":"default","twitter_image_type":"default","twitter_image_url":null,"twitter_image_custom_url":null,"twitter_image_custom_fields":null,"twitter_title":null,"twitter_description":null,"schema":{"blockGraphs":[],"customGraphs":[],"default":{"data":{"Article":[],"Course":[],"Dataset":[],"FAQPage":[],"Movie":[],"Person":[],"Product":[],"ProductReview":[],"Car":[],"Recipe":[],"Service":[],"SoftwareApplication":[],"WebPage":[]},"graphName":"WebPage","isEnabled":true},"graphs":[]},"schema_type":"default","schema_type_options":null,"pillar_content":false,"robots_default":true,"robots_noindex":false,"robots_noarchive":false,"robots_nosnippet":false,"robots_nofollow":false,"robots_noimageindex":false,"robots_noodp":false,"robots_notranslate":false,"robots_max_snippet":"-1","robots_max_videopreview":"-1","robots_max_imagepreview":"large","priority":null,"frequency":"default","local_seo":null,"seo_analyzer_scan_date":"2025-10-20 13:08:29","breadcrumb_settings":null,"limit_modified_date":false,"open_ai":null,"ai":null,"created":"2024-05-30 19:04:41","updated":"2025-10-20 13:08:29"},"aioseo_breadcrumb":"<div class=\"aioseo-breadcrumbs\"><span class=\"aioseo-breadcrumb\">\n\t\t\t<a href=\"https:\/\/inimmune.com\" title=\"Home\">Home<\/a>\n\t\t<\/span><span class=\"aioseo-breadcrumb-separator\">&raquo;<\/span><span class=\"aioseo-breadcrumb\">\n\t\t\tTRAC478 Vaccine Adjuvant\n\t\t<\/span><\/div>","aioseo_breadcrumb_json":[{"label":"Home","link":"https:\/\/inimmune.com"},{"label":"TRAC478 Vaccine Adjuvant","link":"https:\/\/inimmune.com\/?page_id=609"}],"_links":{"self":[{"href":"https:\/\/inimmune.com\/index.php?rest_route=\/wp\/v2\/pages\/609","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/inimmune.com\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/inimmune.com\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/inimmune.com\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/inimmune.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=609"}],"version-history":[{"count":0,"href":"https:\/\/inimmune.com\/index.php?rest_route=\/wp\/v2\/pages\/609\/revisions"}],"wp:attachment":[{"href":"https:\/\/inimmune.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=609"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}